SlimStem - Actv Biotech

Actv Biotech

An Anti-Cellulite
Active Ingredient

Origin

ProliCell® SlimStem developed by ACTV Biotechnology via combined with ProliCell® AvocStem, ProliCell® Almond, ProliCell® IsoStem and ProliCell® Centella.

What is ProliCell® Technology?

ProliCell® Technology enables to benefit the effects of plant stem cells and small RNAs in their vesicles

Effect Mechanism:

ProliCell® SlimStem contains enriched stem cell components and stem cell specific exogenous small RNAs thanks to the elicitor application.
ProliCell SlimStem strengthen connective tissue by stimulates collagen and elastin synthesis.
ProliCell SlimStem promotes lipolysis and inhitbits adipogenesis, thereby aiding in the reduction of cellulite by decreasing the number and size of adipocytes.
ProliCell SlimStem increases microcirculation

How Does ProliCell
SlimStem Effect?

In Vivo Efficiency Test

A study was conducted on 24 healthy female volunteers aged between 20 and 56 with cellulite problems in the hip/thigh areas. The volunteers were divided into two groups: 12 received a placebo, and 12 received a formulation containing 2% ProliCell SlimStem, applied twice a day, morning and evening, for 56 days.

Measurements were recorded before starting treatment (T0), after 4 weeks of treatment (T28), and after 8 weeks of treatment (T56).

After 56 days, the formulation was found to increase skin hydration by 93.2%, improve elasticity by 83.1%, reduce porosity by 62%, and decrease the appearance of cellulite by 53.3% compared to the placebo.

Ancient Botanicals, Modern Innovation: The Science Behind ProliCell® SlimStem

Harnessing the wisdom of ancient civilizations, ProliCell® SlimStem unites the power of nature’s most revered botanicals with groundbreaking cellular science. For centuries, Avocado, Almond, Soy, and Centella asiatica have been treasured for their ability to nourish, heal, and rejuvenate the skin. Now, their potent bioactive compounds are amplified with small RNA-loaded extracellular vesicles, precisely designed to enhance skin firmness and reduce the appearance of cellulite.

Across cultures and eras, these botanicals have been symbols of vitality and beauty. The Aztecs, Incas, and Mayans harnessed avocado for its deeply hydrating and restorative properties, while Ottoman women revered its oil as the “food of heaven.” Almonds, discovered in ancient Egyptian tombs, were prized for their protective and rejuvenating effects, enriching the skin with essential nutrients. In the Far East, soy was revered as “breeding gold,” its isoflavones supporting collagen synthesis and youthful radiance. Meanwhile, Centella asiatica, known as “Tiger Herb,” was celebrated in Ayurveda and Traditional Chinese Medicine for its remarkable ability to heal, regenerate, and enhance microcirculation.

By drawing from this rich botanical heritage, ProliCell® SlimStem redefines skincare with an innovative approach that stimulates anti-cellulite gene expression. This advanced formulation promotes collagen and elastin synthesis, improves microcirculation, and accelerates cellular renewal. The result is a firmer, smoother, and more revitalized skin experience—a perfect harmony of tradition and modern scientific excellence.

SlimStem

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SlimStem: Technical Document

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